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Table 2 Human radiation dosimetry estimates for 18F radioactivity extrapolated from the rat ex vivo data

From: Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, 18F-labeled [Nle14,Lys40]exendin-4 analog, shows promise for clinical imaging

Organ

Dose (mSv/MBq)

Adrenal glands

0.016

Brain

0.004

Breasts

0.004

Gallbladder wall

0.011

LLI wall

0.003

Small intestine

0.005

Stomach wall

0.007

ULI wall

0.005

Heart wall

0.010

Kidneys

0.300

Liver

0.026

Lungs

0.071

Muscle

0.005

Ovaries

0.003

Pancreas

0.023

Red bone marrow

0.009

Osteogenic cells

0.045

Skin

0.003

Spleen

0.022

Testes

0.001

Thymus

0.005

Thyroid

0.003

Urinary bladder wall

0.002

Uterus

0.003

Total body

0.009

Effective dose

0.021

  1. LLI lower large intestine wall, ULI upper large intestine