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EJNMMI Research
Fig. 8 | EJNMMI Research

Fig. 8

From: Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, 18F-labeled [Nle14,Lys40]exendin-4 analog, shows promise for clinical imaging

Fig. 8

Islet labeling in human pancreas after [18F]exendin-4 incubation in vitro. a–b Insulin immunohistochemistry confirmed that tracer binding co-localized with the islets. c–d The specificity of [18F]exendin-4 to GLP-1R in the islets was demonstrated by incubating the sections with excess cold exendin-3. Scale bars 1000 μm

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