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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, 18F-labeled [Nle14,Lys40]exendin-4 analog, shows promise for clinical imaging

Fig. 2

Ex vivo measurements of the accumulation of exendin-based tracers in rat pancreas. a In the pancreas (dashed line), the radioactivity uptake of [18F]exendin-4 was rather constant over the course of the study (N = 2–11 rats/time point). b The [18F]exendin-4 uptake (highlighted with a blue box) in the pancreas was significantly higher (P = 0.0001) than uptake of the 64Cu- and 68Ga-labeled PET tracer counterparts (one-way ANOVA) [3]. Conversely, the uptake of the [111In]exendin-4 SPECT tracer (grey) was higher than uptake of the PET tracers [2]

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