Fig. 1From: Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, 18F-labeled [Nle14,Lys40]exendin-4 analog, shows promise for clinical imagingProduction of [18F]exendin-4. 18F-fluoride (aqueous) and tosylate (1) were combined in a nucleophilic reaction for 18F-prelabeling; the product, 18F-fluoro-propargyl-triethylene glycol, was attached to exendin-4-azide (2) via Cu(I)-catalyzed alkyne/azide cycloaddition to produce radiofluorinated exendin-4Back to article page