Fig. 6
Effects of acetaminophen on biochemical parameters for renal function in the rat. Blood and urine samples were collected 2, 6, and 24 h after the administration of acetaminophen. Urine was centrifuged to remove suspended material and the supernatants analyzed to measure total urinary protein (a), creatinine (b), and NAG (d). Blood samples were collected 2, 6, and 24 h after the administration of acetaminophen, and the serum fraction separated from the blood was used for the assay of BUN (c). *p < 0.05 vs. vehicle, # p < 0.05 vs. 100 mg/kg acetaminophen