Fig. 6From: Improved safety and efficacy of 213Bi-DOTATATE-targeted alpha therapy of somatostatin receptor-expressing neuroendocrine tumors in mice pre-treated with l-lysineDose-effect relation between mean renal radiation absorbed dose and the percentage of mice that died before the end of the experiment at 90 days. LD50 kidney dose was 20 ± 8 Gy, a threshold LD5 = 11 ± 4 Gy (P = <0.001). All points represent at least three miceBack to article page