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Table 2 PSA parameters and Gleason scores of patients with negative or positive PET/CT, in subgroups of patients treated with initial or salvage radiation therapy

From: Predictive factors of 18F-choline PET/CT positivity in patients with prostate cancer recurrence after radiation therapy: is the impact of PSA nadir underestimated?

 

Total

Positive PET/CT

Negative PET/CT

p value

Initial radiotherapy

N = 28

N = 23

N = 5

 

 Trigger PSA

9.39 (1.32–111.60)

9.50 (2.04–111.60)

8.50 (1.32–83.40)

0.76

 Relative PSA

8.49 (0.41–104.59)

8.59 (2.03–104.59)

4.00 (0.41–82.97)

0.47

 Gleason score ≤6

12 (43)

10 (44)

2 (40)

1.00*

 Gleason score >6

16 (57)

13 (56)

3 (60)

 

 PSAdt >6 months

9 (32)

7 (30)

2 (60)

1.00*

 PSAdt ≤6 months

19 (68)

16 (70)

3 (40)

 

Salvage radiotherapy

N = 26

N = 17

N = 9

 

 Trigger PSA

5.53 (0.47–18.62)

7.81 (2.60–18.62)

3.85 (0.47–15.01)

0.009

 Relative PSA

5.26 (0.24–17.62)

7.51 (1.85–17.62)

1.69 (0.24–5.09)

0.0004

 Gleason score ≤6

7 (27)

5 (29)

2 (22)

1.00*

 Gleason score >6

19 (73)

12 (71)

7 (78)

 

 PSAdt >6 months

15 (58)

8 (47)

7 (80)

0.22*

 PSAdt ≤6 months

11 (42)

9 (53)

2 (20)

 
  1. PSAdt PSA doubling time
  2. *Fisher’s exact test; all others: Mann-Whitney test