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Table 2 PSA parameters and Gleason scores of patients with negative or positive PET/CT, in subgroups of patients treated with initial or salvage radiation therapy

From: Predictive factors of 18F-choline PET/CT positivity in patients with prostate cancer recurrence after radiation therapy: is the impact of PSA nadir underestimated?

  Total Positive PET/CT Negative PET/CT p value
Initial radiotherapy N = 28 N = 23 N = 5  
 Trigger PSA 9.39 (1.32–111.60) 9.50 (2.04–111.60) 8.50 (1.32–83.40) 0.76
 Relative PSA 8.49 (0.41–104.59) 8.59 (2.03–104.59) 4.00 (0.41–82.97) 0.47
 Gleason score ≤6 12 (43) 10 (44) 2 (40) 1.00*
 Gleason score >6 16 (57) 13 (56) 3 (60)  
 PSAdt >6 months 9 (32) 7 (30) 2 (60) 1.00*
 PSAdt ≤6 months 19 (68) 16 (70) 3 (40)  
Salvage radiotherapy N = 26 N = 17 N = 9  
 Trigger PSA 5.53 (0.47–18.62) 7.81 (2.60–18.62) 3.85 (0.47–15.01) 0.009
 Relative PSA 5.26 (0.24–17.62) 7.51 (1.85–17.62) 1.69 (0.24–5.09) 0.0004
 Gleason score ≤6 7 (27) 5 (29) 2 (22) 1.00*
 Gleason score >6 19 (73) 12 (71) 7 (78)  
 PSAdt >6 months 15 (58) 8 (47) 7 (80) 0.22*
 PSAdt ≤6 months 11 (42) 9 (53) 2 (20)  
  1. PSAdt PSA doubling time
  2. *Fisher’s exact test; all others: Mann-Whitney test