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EJNMMI Research
Fig. 3 | EJNMMI Research

Fig. 3

From: Comparison of the image-derived radioactivity and blood-sample radioactivity for estimating the clinical indicators of the efficacy of boron neutron capture therapy (BNCT): 4-borono-2-18F-fluoro-phenylalanine (FBPA) PET study

Fig. 3

Correlation between blood sampling radioactivity and image-derived radioactivity in each blood pool. The blood samplings radioactivity (BS) at 3, 20, 30 and 50 min after the tracer injection and the image-derived blood radioactivity (PET) at each site (ascending aorta, aortic arch, pulmonary artery, left and right ventricle, inferior vena cava and abdominal aorta) in mid-scan time at 3.8, 20.5, 28.8 and 53 min after the injection were compared. BS is plotted on the horizontal axis, and PET is plotted on the vertical axis. Both units are in cps/g. A linear relationship was found between blood sampling radioactivity and PET image-derived radioactivity in each blood pool (p < 0.001). Strong correlations were observed between these parameters at 20 min after FBPA administration. The image-derived radioactivity measured in the left ventricle and right ventricle 30 min after injection showed high correlation (0.97 and 0.99, respectively), slope close to be 1.0 (0.96 and 0.95, respectively), and intercept (-161 and -149) with blood radioactivity

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