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Table 3 Test-retest analysis of SUV relative to cerebellar activity (SUVRC)

From: Test-retest analysis of a non-invasive method of quantifying [11C]-PBR28 binding in Alzheimer’s disease

 

Mean Test Value

Mean Retest Value

Mean regional difference % (SD)

Mean VAR % (SD)a

ICC

Sample size to detect 5 % changeb

Sample size to detect 10 % changeb

Frontal lobe

0.93

0.96

3.78

(7.63)

−3.50

(7.06)

0.69

27

9

Parietal lobe

0.89

0.93

4.62

(6.37)

−4.37

(5.94)

0.70

20

7

Temporal lobe

0.89

0.92

3.23

(5.87)

−3.05

(5.22)

0.68

17

6

Occipital lobe

0.92

0.94

3.04

(4.98)

−2.90

(4.75)

0.71

13

5

Hippocampus

0.81

0.84

4.44

(8.18)

−4.11

(7.54)

0.77

31

10

Parahippocampus

0.87

0.92

5.46

(9.51)

−5.00

(8.59)

0.38

40

12

Posterior cingulate

0.99

1.05

5.65

(7.25)

−5.31

(6.65)

0.79

25

8

Amygdala

0.92

0.95

4.18

(11.53)

−3.62

(10.51)

0.47

25

8

Mean (SD)

0.90

(0.05)

0.94

(0.06)

4.30

(7.66)

−3.98

(7.07)

0.65

25

8

  1. ICC intraclass correlation coefficient
  2. aVAR = absolute variability (%)
  3. bModel parameters: two tailed, power 0.9, alpha 0.05