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Table 2 Area under the receiver operating characteristic (ROC) curve (AUC)

From: The cingulate island sign within early Alzheimer’s disease-specific hypoperfusion volumes of interest is useful for differentiating Alzheimer’s disease from dementia with Lewy bodies

VOIs

AUC ± SE

95 % CI

p a

CISpreC

0.850 ± 0.068

0.688 to 0.947

 

CISmedO

0.873 ± 0.064

0.716 to 0.961

0.589

CISlatO

0.771 ± 0.081

0.598 to 0.896

0.271

CISwO

0.820 ± 0.074

0.654 to 0.929

0.559

Precuneus_AD_VOI

0.618 ± 0.098

0.438 to 0.776

0.016

PCG_AD_VOI

0.716 ± 0.092

0.538 to 0.855

0.078

Medial_Occipital_VOI

0.614 ± 0.102

0.435 to 0.773

0.032

Lateral_Occipital_VOI

0.585 ± 0.100

0.407 to 0.748

0.021

Whole_Occipital_VOI

0.631 ± 0.098

0.451 to 0.787

0.029

  1. VOI volume of interest, SE standard error, CI confidence interval, PCG posterior cingulate gyri, CISmedO PCG_AD_VOI/Medial_Occipital_VOI, CISlatO PCG_AD_VOI/Lateral_Occipital_VOI, CISwO PCG_AD_VOI/Whole_Occipital_VOI
  2. aThe AUCs of the ROC curves were compared to those thresholded with CISpreC [23]. The italicized p values were not significantly different from the AUC thresholded with CISpreC