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Table 1 Tumour models

From: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models

  Tumour Type Origin Model type Host (supplier)
CRUK Cambridge Institute (CI) AsPC-1 Pancreatic Human Xenografta CB17 SCID mouse (Charles River)
  MiaPaCa-2 Pancreatic Human Xenografta CB17 SCID mouse (Charles River)
  PancTu I Pancreatic Human Xenografta CB17 SCID mouse (Charles River)
  Colo-357 Pancreatic Human Xenografta CB17 SCID mouse (Charles River)
  K8484b Pancreatic Murine Syngeneic allografta PC mouse (p53R172H; Pdx1-Cre) (CI)
  KPCc Pancreatic Murine Spontaneousd KPC mouse (KrasG12D; p53R172H; Pdx1-Cre) (CI)
AstraZeneca (AZ) PC9 NSCLC Human Xenografta CB17 SCID mouse (AstraZeneca)
  A431 Squamous carcinoma Human Xenografta ONU mouse (AstraZeneca)
  H1975 NSCLC Human Xenografta ONU mouse (AstraZeneca)
Imperial College London (IC) HCT116 Colorectal Human Xenografta BALB/c nu mouse (Charles River)
WWU Münster A549 NSCLC Human Xenografta NMRI nu mouse (Janvier)
  HTB56 NSCLC Human Xenografta NMRI nu mouse (Janvier)
  EBC1 NSCLC Human Xenografta NMRI nu mouse (Janvier)
  H1975 NSCLC Human Xenografta NMRI nu mouse (Janvier)
WMIC Manchester MDA-MB-231-MFP Breast Human Xenografte CBA nu/nu mouse (University of Manchester)
  A549 NSCLC Human Xenografta CBA nu/nu mouse (University of Manchester)
  HCT116 Colorectal Human Xenografta CBA nu/nu mouse (University of Manchester)
  A2870 Ovarian carcinoma Human Xenografta CBA nu/nu mouse (University of Manchester)
  U87 Glioblastoma Human Xenografta CBA nu/nu mouse (University of Manchester)
  FTC113 Follicular thyroid carcinoma Human Xenografta CBA nu/nu mouse (University of Manchester)
  KHT Sarcoma Murine Syngeneic autografta C3H mouse (University of Manchester)
Radboudumc Nijmegen CC531 Colorectal Rodent Syngeneic liver metastasisf Wag/Rij rats (Charles River)
  1. aSubcutaneous tumours
  2. b[15]
  3. cHingorani SR, Wang L, Multani AS, Combs C, Deramoudt TB, Hruban RH et al. Trp53R172H and KRASG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer cell. 2005;7(5):469–483
  4. dSpontaneous tumours arising in the pancreas
  5. eOrthotopic tumours (mammary fat-pad implant)
  6. fTumours created by intra-hepatic injection