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Table 6 Results from visual lesion classification compared to those from assessment of uptake ratios in 46 metastatic bone lesions

From: Longitudinal analysis of bone metabolism using SPECT/CT and 99mTc-diphosphono-propanedicarboxylic acid: comparison of visual and quantitative analysis

 

Progressive

Stable

Regressive

Discrepant lesions (n)

Reader 1 uptake ratios SPECT/CT

12

20

14

 

Reader 1 planar BS

14

18

14

14

Reader 1 SPECT/CT

10

15

21

16

Reader 2 uptake ratios SPECT/CT

10

22

14

 

Reader 2 planar BS

19

9

18

23

Reader 2 SPECT/CT

18

8

20

19

  1. Lesions (OM) were classified either visually or based on ratios of absolute peak tracer uptake in the OM divided by the mean tracer uptake in the reference region. In this case, a change of more than 30 % in the ratio was rated as a significant increase (=progressive) or decrease (=regressive). All other lesions were classified stable. The listed number of discrepant lesions refers to the comparison of each visual analysis to the quantitative assessment