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Fig. 6 | EJNMMI Research

Fig. 6

From: Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake

Fig. 6

Data from the longitudinal study of A431 xenografts: a Changes in tumor volumes with the days since inoculation. b TACs of the differing uptakes in one A431 xenograft of [methyl-11C]-ZTaq:3638-ST-CH3 (black curve, day 8) and targeting [methyl-11C]-ZEGFR:2377-ST-CH3 (red, blue, and green curves on days 8, 19, and 21, respectively). c SUVmean for the uptake of [methyl-11C]-ZTaq:3638-ST-CH3 measured in the A431 tumors vs. days since inoculation. d Variations in specific uptake (SUVmean(ZEGFR:2377)–SUVmean(ZTaq:3638)) with the growth of all ten xenografts from inoculation. e Variations in specific uptake (SUVmean of ZEGFR:2377–SUVmean of ZTaq:3638) of all ten xenografts as their volumes increased. f Variations in specific uptake, SUVmean, in individual xenografts as their volumes increased

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