Reproducibility of 18F-fluoromisonidazole intratumour distribution in non-small cell lung cancer

Grkovski, Milan; Schwartz, Jazmin; Rimner, Andreas; Schöder, Heiko; Carlin, Sean D.; Zanzonico, Pat B.; Humm, John L.; Nehmeh, Sadek A.

doi:10.1186/s13550-016-0210-y

EJNMMI Research

Table 2 Summary of FMISO PET reproducibility analysis in patients with non-small cell lung cancer

From: Reproducibility of ¹⁸F-fluoromisonidazole intratumour distribution in non-small cell lung cancer

Patient (lesion)	TV (cm³)	Scan time pi (min)		SUV_lung		SUV_muscle		SUV_max		SUV_mean		TBR_max		TBR_mean		HTV (cm³)		r _TV
		FMISO1	FMISO2	FMISO1	FMISO2	FMISO1	FMISO2	FMISO1	FMISO2	FMISO1	FMISO2	FMISO1	FMISO2	FMISO1	FMISO2	FMISO1	FMISO2
1 (1)	9.7	146	144	0.31	0.34	0.86	0.86	1.31	1.13	0.92	0.83	1.53	1.19	1.07	0.87	3.0	0.0	0.83
2 (2)	36.6	153	150	0.25	0.26	0.94	0.94	1.86	1.90	1.18	1.34	1.97	1.92	1.25	1.36	19.6	25.7	0.93
3 (3)	15.6	175	178	0.37	0.31	0.94	1.01	1.34	1.52	1.05	1.06	1.37	1.20	1.06	1.02	1.8	0.1	0.72
4 (4)	41.6	179	183	0.38	0.39	1.28	1.20	1.52	1.62	1.26	1.18	1.50	1.56	1.13	1.14	13.8	13.7	0.52
4 (5)	20.1							1.64	2.11	1.23	1.42	1.50	2.02	1.13	1.27	7.7	11.1	0.83
5 (6)	52.3	171	176	0.16	0.19	1.14	1.22	2.05	2.08	1.35	1.49	1.56	1.48	1.03	1.07	9.2	10.0	0.87
5 (7)	33.5							1.95	2.00	1.28	1.39	1.48	1.44	0.97	1.00	5.8	7.8	0.95
5 (8)	7.0							1.15	1.24	0.92	1.02	0.88	0.89	0.70	0.73	0.0	0.0	0.92
6 (9)	110.6	161	165	0.36	0.37	1.03	1.08	1.50	1.58	1.20	1.27	1.50	1.46	1.20	1.18	65.1	56.9	0.80
7 (10)	19.4	156	158	0.32	0.31	1.04	0.98	1.51	1.35	1.19	1.11	1.24	1.17	0.97	0.96	0.3	0.0	0.87
7 (11)	7.5							1.40	1.52	1.15	1.21	1.15	1.31	0.94	1.04	0.0	1.0	0.91
8 (12)	31.6	166	182	0.40	0.38	0.91	0.87	1.42	1.34	0.98	0.99	1.41	1.38	0.97	1.02	1.5	2.3	0.72
8 (13)	61.0							2.19	1.85	1.25	1.21	2.16	1.91	1.23	1.25	30.7	32.6	0.92
8 (14)	17.1							1.90	1.85	1.15	1.11	1.88	1.91	1.14	1.14	6.7	6.8	0.94
8 (15)	4.1							1.05	0.87	0.74	0.69	1.04	0.90	0.73	0.71	0.0	0.0	0.83
9 (16)	23.5	165	148	0.32	0.27	0.91	0.83	1.22	0.91	0.90	0.64	1.11	0.96	0.81	0.68	0.0	0.0	0.81
10 (17)	12.9	164	147	0.28	0.31	1.01	1.06	1.12	1.20	0.83	0.94	1.29	1.30	0.95	1.02	0.7	1.9	0.90
10 (18)	8.1							0.98	1.12	0.79	0.85	1.13	1.21	0.91	0.92	0.0	0.0	0.88
10 (19)	10.1							0.93	1.06	0.72	0.84	1.06	1.15	0.82	0.91	0.0	0.0	0.80
Maximum	110.6	179	183	0.40	0.38	11.28	1.22	2.19	2.09	1.35	1.49	2.16	2.02	1.25	1.36	65.1	56.9	0.95
Minimum	4.1	146	144	0.16	0.19	0.82	0.83	0.93	0.87	0.72	0.64	0.88	0.89	0.70	0.68	0.0	0.0	0.52
Mean ± SD	27.5 ± 25.7	164 ± 10	163 ± 16	0.32 ± 0.07	0.31 ± 0.06	1.00 ± 0.13	1.01 ± 0.14	1.48 ± 0.37	1.49 ± 0.39	1.06 ± 0.20	1.08 ± 0.25	1.41 ± 0.33	1.39 ± 0.35	1.00 ± 0.16	1.02 ± 0.19	9 ± 16	9 ± 15	0.84 ± 0.10
Pearson correlation		0.77		0.91		0.89		0.89		0.90		0.87		0.90		0.99

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