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EJNMMI Research

Table 3 [18F]FPyKYNE-losartan PET binding parameters in sham and Nx rats at 8–10 weeks post-surgery

From: Decreased renal AT1 receptor binding in rats after subtotal nephrectomy: PET study with [18F]FPyKYNE-losartan

 

KBR (unitless)

SUV (g/ml)

DV (ml/cm3)

Sham

8.0 ± 1.7

2.8 ± 0.9

2.9 ± 0.4

Nx

5.7 ± 1.2*

2.1 ± 0.5*

2.3 ± 0.4*

  1. Data is presented as mean ± S.D.
  2. Nx 5/6 nephrectomy, KBR kidney-to-blood ratio, SUV standardized uptake value, DV distribution volume
  3. *p < 0.05 vs sham animals; two-tailed t test
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