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Table 3 [18F]FPyKYNE-losartan PET binding parameters in sham and Nx rats at 8–10 weeks post-surgery

From: Decreased renal AT1 receptor binding in rats after subtotal nephrectomy: PET study with [18F]FPyKYNE-losartan

  KBR (unitless) SUV (g/ml) DV (ml/cm3)
Sham 8.0 ± 1.7 2.8 ± 0.9 2.9 ± 0.4
Nx 5.7 ± 1.2* 2.1 ± 0.5* 2.3 ± 0.4*
  1. Data is presented as mean ± S.D.
  2. Nx 5/6 nephrectomy, KBR kidney-to-blood ratio, SUV standardized uptake value, DV distribution volume
  3. *p < 0.05 vs sham animals; two-tailed t test