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Table 2 Characteristics and hemodynamic data in sham and Nx rats at 8–10 weeks post-surgery (n = 4–5 per group)

From: Decreased renal AT1 receptor binding in rats after subtotal nephrectomy: PET study with [18F]FPyKYNE-losartan

  SBP (mmHg) Plasma Cr (mg/dl) Urine albumin/Cr (ug/mg) Plasma Ang II (pg/ml) Kidney Ang II (pg/mg)
Sham 145.7 ± 18 0.67 ± 0.3 28 ± 1.3 36.53 ± 17.8 16.56 ± 10
Nx 188.4 ± 15.6* 1.36 ± 0.2* 33.66 ± 4.9 11.2 ± 3* 10.47 ± 1.9
  1. Data is presented as mean ± S.D.
  2. Nx 5/6 nephrectomy, BW body weight, SBP systolic blood pressure, Cr creatinine, Ang II angiotensin II
  3. *p < 0.05 vs sham animals; two-tailed t test