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Fig. 2 | EJNMMI Research

Fig. 2

From: A dual tracer 68Ga-DOTANOC PET/CT and 18F-FDG PET/CT pilot study for detection of cardiac sarcoidosis

Fig. 2

18F-FDG PET/CT false positive for cardiac sarcoidosis. Left panel: MIPs of patient no. 15 scanned after injection of ~370 MBq 18F-FDG and ~300 MBq 68Ga-DOTANOC. There was avid an 18F-FDG uptake in all areas of the bone marrow and the spleen indicating long-term infection. A few lymph nodes are visible in the upper mediastinum on the 68Ga-DOTANOC scan. Right panel: transaxial and coronal slices of the cardiac region revealed avid 18F-FDG uptake in the area around the aortic ostium (yellow arrows) which is often seen in aortic valve sclerosis, but can also be mistaken for uptake in a sarcoid lesion (SUVmax 7.6). Clear calcifications are seen around the posterior valve on the low-dose CT. On the 68Ga-DOTANOC scan (bottom), there is no activity above background in the myocardium. By contrast, activity is increased in the pericardium (yellow arrows) and some pericardial fluid is visible indicating pericarditis

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