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Table 1 Time-integrated activity coefficients (TIACs—unit, h) values for the selected organs of each pigs and respective standard deviations (SD)

From: 177Lu-OPS201 targeting somatostatin receptors: in vivo biodistribution and dosimetry in a pig model

Organs

Pig 1

Pig 2

Pig 3

Pig 4

Pig 5

Mean ± SD (n = 5)

Whole body

81.73

72.23

60.95

75.09

80.08

74.02 ± 8.24

Remainder

44.63

53.95

41.46

47.32

45.17

46.51 ± 4.66

Liver

4.98

3.48

2.66

4.51

5.57

4.24 ± 1.17

R. kidney

4.76

3.29

4.69

7.82

2.94

4.70 ± 1.93

L. kidney

4.57

4.18

4.11

7.59

3.14

4.72 ± 1.69

Kidneysa

9.34

7.47

8.80

15.40

6.07

9.42 ± 3.58c

Heart

0.53

3.89

0.41

0.79

0.65

1.25 ± 1.48

Bladder contents

0.90

0.43

0.02

5.27

0.51

1.43 ± 2.17

Spine

4.03

0.57

1.42

0.29

4.16

2.10 ± 1.87

Boneb

21.22

3.00

7.47

1.55

21.91

11.03 ± 9.86

Red marrow

0.12

0.01

0.13

0.22

0.18

0.13 ± 0.08

  1. aSum of both kidneys
  2. bDerived from spine values (19 % of the total skeleton mass)
  3. cMean ± SD values for the kidneys without pig 4 values are 7.92 ± 1.46 h