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Fig. 2 | EJNMMI Research

Fig. 2

From: The effect of dimethyl sulfoxide on the induction of DNA strand breaks in plasmid DNA and colony formation of PC Cl3 mammalian cells by alpha-, beta-, and Auger electron emitters 223Ra, 188Re, and 99mTc

Fig. 2

Calculated numbers of SSB (a, b) and DSB (c, d) per plasmid molecule in the absence (a, c) and presence (b, d) of 0.2 M DMSO for 223Ra, 188Re, and 99mTc. The mean numbers of SSB and DSB were calculated based on the fluorescence intensities shown in Fig. 1. Panel a shows only dose points up to 180 Gy because after higher doses, the SC plasmid forms disappeared. Error bars were calculated by the propagation of uncertainty of the standard error of the mean

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