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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: The effect of dimethyl sulfoxide on the induction of DNA strand breaks in plasmid DNA and colony formation of PC Cl3 mammalian cells by alpha-, beta-, and Auger electron emitters 223Ra, 188Re, and 99mTc

Fig. 1

Dose response of 223Ra (a), 188Re (b), and 99mTc (c) in the absence or presence of DMSO. Dose-dependent increase in open circular DNA and linear DNA was accompanied by the loss of supercoiled DNA. The influence of DMSO on yields of DNA conformational changes shows prevention of SSB and DSB. Error bars present the standard errors of the means from three independent experiments

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