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Table 2 Overview of the average SUVs (±SEM) in the non-ischemic and ischemic hind limb and the average ratio (±SEM) calculated from SPECT scans in the 99mTc-sestamibi and 99mTc-PyP group per time point

From: Comparison of LDPI to SPECT perfusion imaging using 99mTc-sestamibi and 99mTc-pyrophosphate in a murine ischemic hind limb model of neovascularization

SPECT
99mTc-sestamibi group
Time point SUV non-ischemic SUV ischemic ± SEM Ratio ± SEM p value N
Baseline 0.30 ± 0.04 0.29 ± 0.04 0.97 ± 0.05 NS 7
Post-operatively 0.27 ± 0.04 0.16 ± 0.04 0.54 ± 0.10 p = 0.007 7
Day 3 0.24 ± 0.04 0.13 ± 0.04 0.50 ± 0.11 p = 0.006 6
Day 7 0.30 ± 0.04 0.28 ± 0.04 0.93 ± 0.10 NS 7
Day 14 0.26 ± 0.04 0.21 ± 0.04 0.81 ± 0.05 p = 0.022 7
99mTc-PyP group
Time point SUV non-ischemic SUV ischemic Ratio p value N
Baseline 0.17 ± 0.03 0.15 ± 0.03 0.92 ± 0.04 NS 6
Post-operatively 0.15 ± 0.04 0.35 ± 0.17 3.08 ± 1.50 NS 6
Day 3 0.16 ± 0.04 0.57 ± 0.08 4.93 ± 1.25 p = 0.004 5
Day 7 0.13 ± 0.04 0.42 ± 0.10 3.27 ± 0.19 p = 0.013 5
Day 14 0.16 ± 0.07 0.18 ± 0.06 1.21 ± 0.21 NS 3
  1. Represented p values indicate the difference compared to the non-ischemic limb
  2. NS non-significant, N the number of animals available for analysis