EJNMMI Research

Table 2 Overview of the average SUVs (±SEM) in the non-ischemic and ischemic hind limb and the average ratio (±SEM) calculated from SPECT scans in the ^99mTc-sestamibi and ^99mTc-PyP group per time point

From: Comparison of LDPI to SPECT perfusion imaging using ^99mTc-sestamibi and ^99mTc-pyrophosphate in a murine ischemic hind limb model of neovascularization

SPECT
^99mTc-sestamibi group
Time point	SUV non-ischemic	SUV ischemic ± SEM	Ratio ± SEM	p value	N
Baseline	0.30 ± 0.04	0.29 ± 0.04	0.97 ± 0.05	NS	7
Post-operatively	0.27 ± 0.04	0.16 ± 0.04	0.54 ± 0.10	p = 0.007	7
Day 3	0.24 ± 0.04	0.13 ± 0.04	0.50 ± 0.11	p = 0.006	6
Day 7	0.30 ± 0.04	0.28 ± 0.04	0.93 ± 0.10	NS	7
Day 14	0.26 ± 0.04	0.21 ± 0.04	0.81 ± 0.05	p = 0.022	7
^99mTc-PyP group
Time point	SUV non-ischemic	SUV ischemic	Ratio	p value	N
Baseline	0.17 ± 0.03	0.15 ± 0.03	0.92 ± 0.04	NS	6
Post-operatively	0.15 ± 0.04	0.35 ± 0.17	3.08 ± 1.50	NS	6
Day 3	0.16 ± 0.04	0.57 ± 0.08	4.93 ± 1.25	p = 0.004	5
Day 7	0.13 ± 0.04	0.42 ± 0.10	3.27 ± 0.19	p = 0.013	5
Day 14	0.16 ± 0.07	0.18 ± 0.06	1.21 ± 0.21	NS	3

Represented p values indicate the difference compared to the non-ischemic limb
NS non-significant, N the number of animals available for analysis

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