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EJNMMI Research

Table 3 Volume of activity quartiles and areas under the cumulative activity curves

From: Evaluation of pulmonary perfusion by SPECT imaging using an endothelial cell tracer in supine humans and dogs

  

Dorsoventral

Caudocranial

Mediolateral

VAQ25 (%)

PulmoBind-humans

20.9 ± 0.4

23.3 ± 0.2

27.8 ± 0.2

PulmoBind-dogs

21.6 ± 0.5

22.1 ± 1.1

28.8 ± 0.5*

VAQ50 (%)

PulmoBind-humans

45.2 ± 0.6

44.4 ± 0.3

51.6 ± 0.2

PulmoBind-dogs

43.5 ± 0.6

42.4 ± 1.1*

54.1 ± 0.5**

VAQ75 (%)

PulmoBind-humans

72.4 ± 0.4

67.9 ± 0.4

74.2 ± 0.2

PulmoBind-dogs

68.0 ± 0.4***

66.6 ± 0.9

76.1 ± 0.2**

AUC-5000 (%2)

PulmoBind-humans

302 ± 34

395 ± 25

−92.5 ± 15.8

PulmoBind-dogs

452 ± 39*

502 ± 80

−223 ± 21**

  1. Cumulative voxels representing 25 % (VAQ25), 50 % (VAQ50) and 75 % (VAQ75) of cumulative 99mTc-PulmoBind activity for each axis. AUC-5000 represents the deviation from a line of identity indicative of a positive or negative gradient vs. PulmoBind-humans
  2. *p < .05, **p < .01, ***p < .001 vs. PulmoBind-humans
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