18F-fluoride-PET for dynamic in vivo monitoring of bone formation in multiple myeloma

EJNMMI Research

Table 1 ¹⁸F-uptake per patient before and after treatment

	¹⁸F-uptake (SUV_A50%)			Disease response according to IMWG criteria
		Before treatment	After treatment	Disease response according to IMWG criteria
BBR01	Minimum	7.34	12.50	Stable disease
	Maximum	11.34	17.49
	Biopsy^a	11.34	13.09
BBR04	Minimum	9.19	7.09	Stable disease
	Maximum	15.74	16.00
	Biopsy^a	5.86	10.60
BBR05	Minimum	6.74	6.14	Partial response
	Maximum	37.92	37.67
	Biopsy^a	6.42	6.19
BBR06	Minimum	4.42	2.71	Partial response
	Maximum	16.89	17.29
	Biopsy^a	7.32	6.56
BBR07	Minimum	8.86	7.13	Very good partial response
	Maximum	19.26	18.69
	Biopsy^a	5.91	4.31

^aThis value represents the ¹⁸F-uptake at the iliac crest, which was compared with MAR. It does not represent a MM bone lesion, except in patient BBR01