From: PET imaging of cyclooxygenase-2 (COX-2) in a pre-clinical colorectal cancer model
[18F]Pyricoxib | [18F]Pyricoxib + 2 mg celecoxib | |
---|---|---|
Organ | ||
Blood | 0.65 ± 0.12 | 0.98 ± 0.09 |
Heart | 2.52 ± 0.54 | 5.70 ± 1.58 |
Lung | 3.75 ± 0.66 | 52.26 ± 43.08 |
Liver | 17.13 ± 1.22 | 25.47 ± 2.44 |
Kidneys | 4.38 ± 1.01 | 8.40 ± 0.77 |
Spleen | 1.24 ± 0.33 | 2.72 ± 0.65 |
Stomach | 1.08 ± 0.29 | 3.96 ± 2.73 |
Duodenum | 4.59 ± 0.73 | 5.18 ± 1.31 |
Intestine (small) | 8.08 ± 2.33 | 6.66 ± 1.95 |
Intestine (large) | 4.21 ± 1.74 | 3.48 ± 0.80 |
Pancreas | 3.92 ± 1.39 | 7.22 ± 2.87 |
Bone | 0.67 ± 0.19 | 1.05 ± 0.16 |
Ovaries | 8.22 ± 1.27 | 4.97 ± 2.84 |
Brain | 1.74 ± 0.51 | 3.79 ± 0.56 |
Fat | 12.67 ± 5.45 | 5.80 ± 3.84 |
Muscle | 1.42 ± 0.54 | 1.59 ± 0.64 |
HCA-7 tumor | 2.12 ± 0.53 | 1.04 ± 0.30** |
Tumor/muscle | 1.81 ± 1.04 | 0.70 ± 0.19 |
Tumor/blood | 3.39 ± 0.55 | 1.09 ± 0.41 |