Table 1 Model parameters and start values of the fitting parameters

R _K [nmol]

1.4^a

2.1 ± 0.8^b

R _L [nmol]

2.1^a

1.8 ± 0.7^b

R _S [nmol]

3.8^a

3.5 ± 3.1^b

R _R [nmol]

6.4^a

7.3 ± 2.5^b

V _T [l]

0.3^a

0.2 ± 0.3^b

f _T [ml/min/g]

0.2 ± 0.1^b

0.25 ± 0.06^b

f _ex [%]

96 ± 1.0^b

96^c

GFR [ml/min]

57.4^a

64.4 ± 15.1^b

λ _deg,T [10⁻⁴/min]

1.1^a

1.5 ± 0.6^b

λ _deg,K [10⁻⁴/min]

1.1 ± 0.1^b

1.1^c

λ _deg,L [10⁻⁴/min]

0.5 ± 0.1^b

0.5^c

λ _deg,S [10⁻⁴/min]

1.6 ± 0.1^b

1.6^c

λ _deg,R [10⁻⁴/min]

1.3 ± 0.1^b

1.3^c

# of fitting parameters

13

8