Fig. 7
From: αVβ3 integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice
Immunostaining of inflammation and αV integrin. a Significant correlation between percent area of CD68 staining and percent area of CD51 staining (Pearson’s r = 0.73, P = 0.04). Histopathological characterization of the aortic tissue section from an atherosclerotic animal. b Merged image of CD68 (macrophages in green) and CD51 (αV integrin in red) co-labeling. High-power views (corresponding to the box in b) showing representative micrographs of co-labeling (c), macrophage (d), and αV integrin (e). Arrows point to cells positive for both markers. Nuclei were stained with 4′,6-diamidino-2-phenylindole (blue) (c). Scale bar = 20 μm in b. Scale bar = 10 μm in c–e