Fig. 6
From: αVβ3 integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice
Autoradiographic analysis of 99mTc-maraciclatide uptake. 99mTc-maraciclatide uptake is obvious in the aorta of the ApoE−/− mouse (a) while a minimal tracer uptake corresponding to background activity is identified in the aorta of the C57BL/6 control mouse (b). Higher tracer uptake in the aortas of ApoE−/− mice was confirmed by drawing regions of interest around the aortic cross (c). P value on top of the graph indicates the Mann-Whitney test result between the two experimental groups. Ctrl control