Fig. 2

Reference voxels extracted from cortical gray matter of a representative Alzheimer’s disease patient (AD, top row) and a healthy control subject (HC, bottom row). On transaxial (left) and coronal (right) \( {BP}_{\mathsf{ND}}^{\ast } \) parametric images, areas surrounded by red lines indicate voxels with \( {BP}_{\mathsf{ND}}^{\ast } \) values above mean −2 SD in this subject for a range of the mean FWHM in HCs (0.33). To obtain reference voxels (light green area) extracted from cerebral and cerebellar cortical gray matter, we intersected the red area with gray matter voxels segmented on magnetic resonance images