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Table 1 Organ absorbed dose per injected activity (Gy/MBq) for 177Lu-m11B6 based on A. 111In-m11B6 and B. 177Lu-m11B6 biokinetics

From: Radioimmunotherapy of prostate cancer targeting human kallikrein-related peptidase 2

 

A. Based on 111In-m11B6

B. Based on 177Lu-m11B6

Organ

Self-dose

Total dose

Self-dose

Total dose

Tumor

2.2

2.3

4.8

4.9

Submand. gland

1.9

2.0

5.6

5.6

Blood

1.3

1.3

1.2

1.3

Bone marrow

0.40

0.47

0.38

0.45

Liver

0.63

0.66

1.56

1.59

Heart

0.47

0.66

0.56

0.74

Lung

0.41

0.54

0.59

0.71

Spleen

0.67

0.71

1.9

1.9

Kidney

0.50

0.53

0.50

0.54

GI tract

0.30

0.35

0.35

0.44

Bone

0.13

0.27

0.18

0.30

Brain

0.017

0.040

0.019

0.041

Testes

0.24

0.28

0.31

0.35