Radiolabel | Antibody | D0 | D2 | D6 |
---|---|---|---|---|
125I- | Wild type | 78.64 ± 1.59a | 59.09 ± 5.54 | 32.36 ± 0.12 |
I253A | 66.76 ± 0.33 | 47.50 ± 2.69 | 30.99 ± 0.77 | |
H310A | 70.75 ± 3.99 | 53.52 ± 3.53 | 32.95 ± 0.28 | |
H435A | 69.50 ± 0.33 | 54.59 ± 4.68 | 34.82 ± 2.98 | |
I253A/H310A | 71.93 ± 3.22 | 58.29 ± 0.33 | 30.52 ± 1.45 | |
111In- | Wild type | 86.84 ± 0.74 | 64.46 ± 8.04 | 40.21 ± 0.62 |
I253A | 83.47 ± 4.26 | 59.16 ± 3.05 | 40.77 ± 0.53 | |
H310A | 81.03 ± 3.38 | 55.83 ± 1.78 | 35.64 ± 0.29 | |
H435A | 83.38 ± 3.81 | 59.70 ± 7.27 | 46.19 ± 4.63 | |
I253A/H310A | 86.07 ± 2.74 | 57.18 ± 11.61 | 42.54 ± 1.15 |