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Table 3 Regional BPND values for radioligands in rat PET

From: Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors

 

Striatum

Hippocampus

[11C]TASP0410457

1.26 ± 0.12

0.53 ± 0.06

[11C]TASP0434988

0.92 ± 0.21

0.36 ± 0.11