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Fig. 7 | EJNMMI Research

Fig. 7

From: Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors

Fig. 7

In vitro autoradiographic labeling of rat and rhesus monkey brain slices with [11C]TASP0410457. The images show radioligand bindings in sagittal rat brain sections without blockade (a) or with 10 μM of unlabelled TASP0410457 (b), thioperamide (c), and ciproxifan (d) and in sagittal monkey brain sections without blockade (e) or with 10 μM of unlabelled TASP0410457 (f) or ciproxifan (g). Scale bar: 10 mm

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