Fig. 4

Simplified uptake parameters. TBR values from the 40–50-min post injection interval, using arterial samples (a) and SUVs from the 40–50-min post injection interval (b) in all patients off and on erlotinib therapy. Correlation between TBR values from the 40–50-min post injection interval, using arterial (c) and venous (d) samples, with V _T in all patients off and on erlotinib therapy. Abbreviations: TBR tumor-to-blood ratio, SUV standardized uptake value, V _T volume of distribution, E− without erlotinib therapy, E+ with erlotinib therapy