Fig. 2

Calculated absorbed radiation dose rates in the tumour and kidney after 10 MBq ²¹³Bi-DOTATATE, based on the data obtained in the biodistribution study. Absorbed dose rate as function of time in H69 tumour-bearing animals; tumour (a) and kidney (b). Same data are shown of the tumour (c) and kidney (d) for CA20948 tumour-bearing animals. Red lines indicate the absorbed dose rate contributed by all alpha particles and blue lines by all beta particles. The dotted lines indicate the individual absorbed dose rate of ²¹³Bi, ²¹³ Po, ²⁰⁹Tl and ²⁰⁹ Pb