Fig. 1

Measurement of parameters. The area at risk (AAR; curved yellow line) and normally perfused area (NA; blue painting) were defined from the ²⁰¹Tl image (a, c), and these ROIs were applied to the ^99mTc-annexin-V images (b, d). Regions of interest were drawn manually over the area with easily identifiable ^99mTc-annexin-V uptake (d, red painting). The ²⁰¹Tl image demonstrates the area at risk, while the ^99mTc-annexin-V image reflects the area and intensity of apoptosis. Each area’s wall thickness was calculated as an average of three radial lines (c, orange line) those equally divided the area into four