Fig. 1
From: Targeting activated hepatic stellate cells (aHSCs) for liver fibrosis imaging
Schematic diagram of activated hepatic stellate cell (aHSCs)-targeted imaging in liver fibrosis. a In normal liver, HSCs are in the quiescent state, i.e., quiescent HSCs (qHSCs). b Following fibrotic stimuli, qHSCs transdifferentiate into activated HSCs (aHSCs). Receptors that are specifically upregulated on aHSCs are potential targets for molecular imaging of liver fibrosis. c Magnified image that demonstrates imaging probes’ specific binding to aHSCs. d Imaging of liver fibrosis