Fig. 2

Comparative biodistribution of [¹¹¹In]- and [¹⁷⁷Lu]PSMA-I&T in LNCaP tumor-bearing mice 1 h p.i. Biodistribution studies were carried out using LNCaP xenograft-bearing CB17 SCID ([¹¹¹In]PSMA-I&T) or CD-1 nu/nu ([¹⁷⁷Lu]PSMA-I&T) mice. Animals were injected intravenously with 1.4 MBq (0.2 nmol) of the respective PSMA-I&T analog. Data are represented as % injected dose per gram tissue (%iD/g) and are means ± SD (groups of n = 5). Animal experiments were conducted in accordance with the German Animal Welfare Act (Deutsches Tierschutzgesetz, approval no. 55.2-1-54-2532-71-13)