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Fig. 2 | EJNMMI Research

Fig. 2

From: Non-invasive molecular imaging of inflammatory macrophages in allograft rejection

Fig. 2

99mTc-SER-4 NanoSPECT/CT imaging and biodistribution of Sn+ macrophages. C57Bl/6 wild-type (WT) mice were imaged a 0.5 h, b 1 h, c 3 h and d 6 h post injection with 99mTc-SER-4. Arrows indicate uptake of tracer by Sn+ macrophages in the spleen (S), liver (L) and bone marrow (BM). After imaging, C57BL/6 wild-type (WT) mice were euthanized and tissues explanted, weighed and gamma counted. Maximum intensity projections are shown. e 99mTc-SER-4 biodistributions at 1, 3 and 6 h post injection were expressed as percentage injected dose per gram of tissue (%ID/g). Error bars represent the standard error of the mean of n = 3

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