Fig. 1

Representative images in animals with and without misinjection. Maximum intensity projection (MIP) visualization of the small animal positron emission tomography/computed tomography (SA-PET/CT) reconstruction for a treated rat in the second experiment without tracer extravasation on day 0 (a) and with tracer extravasation on day 3 (b). On day 3, a volume of interest (VOI) region was manually drawn and a visually adapted. Isocontour was applied (displayed in green) to quantify and correct for tail vein extravasation. Yellow arrows show the subcutaneous tumors