Fig. 4From: Hybrid PET/optical imaging of integrin αVβ3 receptor expression using a 64Cu-labeled streptavidin/biotin-based dimeric RGD peptide a U87MG cellular uptake of the 64Cu-DOTA-(AF)SAv/biotin-PEG-RGD2 as a function of time. b Cellular uptake of the hybrid probe at 21 h into the incubation (black) and after co-incubation with 10 μM of RGD2 (white). Data are means ± SDs from triplicate experiments. **P < 0.01 and ***P < 0.001Back to article page