Fig. 3From: Hybrid PET/optical imaging of integrin αVβ3 receptor expression using a 64Cu-labeled streptavidin/biotin-based dimeric RGD peptideIntegrin αVβ3 receptor binding of the hybrid probe. 125I-RGDyK was used as the radioligand. IC50 values of DOTA-(AF)SAv/biotin-PEG-RGD2 (closed circles) and RGD2 (open circles) were 12.1 ± 4.2 nM and 37.5 ± 18.3 nM, respectively (n = 3)Back to article page