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Table 2 Method II—percentage of tumor peak activity

From: Optimal definition of biological tumor volume using positron emission tomography in an animal model

Cpeak (%) Sensitivity (CI) Specificity (CI) GTAOE/WTAH (CI)
15 100.0 % (99.9–100.0 %) 32.2 % (23.0–42.2 %) 28.3 % (23.0–33.8 %)
20 99.6 % (99.4–99.8 %) 46.9 % (36.1–57.4 %) 18.9 % (15.0–23.0 %)
25 98.7 % (98.1–99.2 %) 57.4 % (47.2–67.1 %) 13.3 % (10.3–16.5 %)
30 96.9 % (95.9–97.8 %) 66.0 % (57.1–74.5 %) 9.3 % (7.0–11.8 %)
35 93.7 % (92.0–95.3 %) 73.8 % (65.8–81.1 %) 6.3 % (4.5–8.3 %)
40 89.0 % (86.4–91.5 %) 80.2 % (73.2–86.5 %) 4.2 % (2.8–5.8 %)
45 83.1 % (79.8–86.1 %) 86.3 % (80.9–91.2 %) 2.7 % (1.8–3.8 %)
50 75.6 % (72.0–79.1 %) 90.8 % (86.5–94.6 %) 1.7 % (1.1–2.5 %)
70 34.1 % (29.5–38.9 %) 98.9 % (98.0–99.6 %) 0.1 % (0.0–0.2 %)
90 8.4 % (5.5–11.6 %) 99.9 % (99.7–99.9 %) 0.0 % (0.0–0.0 %)
  1. CI confidence interval, GTA OE gross tumor area overestimate, WTA H whole tumor areas on histology