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Table 1 Method I—percentage of maximal voxel activity

From: Optimal definition of biological tumor volume using positron emission tomography in an animal model

Cmax(%)

Sensitivity (CI)

Specificity (CI)

GTAOE/WTAH (CI)

15

99.9 % (99.8–100.0 %)

36.3 % (25.9–46.8 %)

25.0 % (20.4–29.9 %)

20

99.4 % (99.1–99.7 %)

50.4 % (39.7–60.7 %)

16.7 % (13.2–20.5 %)

25

98.1 % (97.4–98.8 %)

61.1 % (51.6–70.2 %)

11.3 % (8.7–14.1 %)

30

95.3 % (93.9–96.6 %)

70.9 % (62.7–78.6 %)

7.5 % (5.5–9.8 %)

35

91.3 % (89.2–93.3 %)

77.5 % (70.3–84.2 %)

5.0 % (3.4–6.7 %)

40

85.3 % (82.3–88.2 %)

84.1 % (78.3–89.3 %)

3.1 % (2.0–4.4 %)

45

77.3 % (73.8–80.6 %)

90.0 % (85.8–93.8 %)

1.9 % (1.2–2.7 %)

50

67.2 % (62.9–71.4 %)

93.4 % (90.4–96.2 %)

1.1 % (0.6–1.7 %)

70

23.6 % (19.4–28.4 %)

99.4 % (98.9–99.8 %)

0.1 % (0.0–0.1 %)

90

3.7 % (2.3–5.4 %)

100.0 % (100.0–100.0 %)

0.0 % (0.0–0.0 %)

  1. CI confidence interval, GTA OE gross tumor area overestimate, WTA H whole tumor areas on histology