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Table 1 Method I—percentage of maximal voxel activity

From: Optimal definition of biological tumor volume using positron emission tomography in an animal model

Cmax(%) Sensitivity (CI) Specificity (CI) GTAOE/WTAH (CI)
15 99.9 % (99.8–100.0 %) 36.3 % (25.9–46.8 %) 25.0 % (20.4–29.9 %)
20 99.4 % (99.1–99.7 %) 50.4 % (39.7–60.7 %) 16.7 % (13.2–20.5 %)
25 98.1 % (97.4–98.8 %) 61.1 % (51.6–70.2 %) 11.3 % (8.7–14.1 %)
30 95.3 % (93.9–96.6 %) 70.9 % (62.7–78.6 %) 7.5 % (5.5–9.8 %)
35 91.3 % (89.2–93.3 %) 77.5 % (70.3–84.2 %) 5.0 % (3.4–6.7 %)
40 85.3 % (82.3–88.2 %) 84.1 % (78.3–89.3 %) 3.1 % (2.0–4.4 %)
45 77.3 % (73.8–80.6 %) 90.0 % (85.8–93.8 %) 1.9 % (1.2–2.7 %)
50 67.2 % (62.9–71.4 %) 93.4 % (90.4–96.2 %) 1.1 % (0.6–1.7 %)
70 23.6 % (19.4–28.4 %) 99.4 % (98.9–99.8 %) 0.1 % (0.0–0.1 %)
90 3.7 % (2.3–5.4 %) 100.0 % (100.0–100.0 %) 0.0 % (0.0–0.0 %)
  1. CI confidence interval, GTA OE gross tumor area overestimate, WTA H whole tumor areas on histology