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EJNMMI Research

Table 2 Comparison of 68Ga3+ labelling conditions commonly employed for radiosynthesis of [68Ga(DOTATATE)] and the conditions employed for radiosynthesis of [68Ga(THP-TATE)]

From: Rapid kit-based 68Ga-labelling and PET imaging with THP-Tyr3-octreotate: a preliminary comparison with DOTA-Tyr3-octreotate

Reaction variables

[68Ga(DOTATATE)]

[68Ga(THP-TATE)]

Temperature

80–90 °C

20–25 °C

Time

5–10 min

<2 min

Yield

>95 %

>95 %

pH

3–5

5–7

Amount of conjugate

7–30 nmol

10 nmol

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