Absorption, distribution and excretion of intravenously injected 68Ge/68Ga generator eluate in healthy rats, and estimation of human radiation dosimetry

EJNMMI Research

Table 6 Additional dosimetry estimates based on a male rat distribution data

	Absorbed dose per unit radioactivity administered (mSv/MBq)
Organ	15-year-olds	10-year-olds	5-year-olds	1-year-olds	Newborn
Organ	(50 kg)	(30 kg)	(17 kg)	(10 kg)	(5 kg)
Adrenals	0.0201	0.0313	0.0491	0.0897	0.231
Brain	0.0039	0.00523	0.00723	0.0115	0.0259
Breasts	0.01580	0.0258	0.0416	0.0790	0.195
Gallbladder wall	0.0203	0.0312	0.0483	0.0921	0.228
Lower large intestine wall	0.00149	0.0248	0.0396	0.0746	0.191
Small intestine	0.0167	0.0267	0.0427	0.0818	0.199
Stomach wall	0.0175	0.0275	0.0440	0.0843	0.206
Upper large intestine wall	0.0165	0.0266	0.0428	0.0814	0.202
Heart wall	0.280	0.435	0.700	1.27	2.49
Kidneys	0.0295	0.0421	0.0633	0.113	0.282
Liver	0.0876	0.133	0.199	0.384	0.888
Lungs	0.0352	0.0504	0.0765	0.147	0.374
Muscle	0.0137	0.0253	0.0665	0.134	0.199
Ovaries	0.0175	0.0258	0.0461	0.0799	0.194
Pancreas	0.02060	0.0361	0.0501	0.098	0.275
Red marrow	0.02190	0.0355	0.0643	0.1620	0.630
Osteogenic cells	0.05470	0.0850	0.1390	0.3220	0.974
Skin	0.0121	0.0198	0.0326	0.0639	0.164
Spleen	0.0327	0.0503	0.0801	0.1460	0.378
Testes	0.0185	0.1120	0.1320	0.1810	0.269
Thymus	0.02270	0.0324	0.0501	0.0911	0.214
Thyroid	0.0330	0.0514	0.11	0.206	0.298
Urinary bladder wall	0.0488	0.0760	0.122	0.232	0.6040
Uterus	0.0165	0.0262	0.0424	0.0810	0.197
Total body	0.0220	0.0360	0.0584	0.1150	0.292
Effective dose (mSv/MBq)	0.02530	0.05580	0.081000	0.14600	0.34300