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Table 4 Human residence times and radiation dose estimates for 68Ga radioactivity extrapolated from the rat biodistribution data

From: Absorption, distribution and excretion of intravenously injected 68Ge/68Ga generator eluate in healthy rats, and estimation of human radiation dosimetry

Organ

Residence time (h)

Dose (mSv/MBq)

 

Female rat data

Male rat data

Female rat data

Male rat data

Adrenals

  

0.02210

0.01600

Blood

0.7790

0.3708

  

Bone

0.3120

0.1950

  

Bone marrow

0.0688

0.0425

  

Brain

0.0064

0.0043

0.00591

0.00372

Breasts

  

0.01790

0.01260

Gallbladder wall

  

0.01950

0.01680

Lower large intestine wall

  

0.01520

0.01260

Small intestine

  

0.01480

0.01350

Stomach wall

  

0.01870

0.01400

Upper large intestine wall

  

0.01580

0.01360

Heart wall

0.0117

0.0072

0.50100

0.21600

Kidneys

0.0149

0.0118

0.03360

0.02430

Liver

0.1716

0.2226

0.07220

0.06520

Lungs

0.0591

0.0352

0.05020

0.02450

Muscle

0.4238

0.2484

0.01900

0.00928

Ovaries

0.0006

 

0.03080

0.01290

Pancreas

0.0027

0.0013

0.02860

0.01530

Red marrow

0.0688

0.0425

0.02530

0.01850

Osteogenic cells

  

0.07580

0.04180

Skin

  

0.01170

0.0097300

Spleen

0.0081

0.0069

0.03370

0.02280

Thymus

  

0.03050

0.01860

Thyroid

0.0008

0.0005

0.02640

0.02100

Testes

 

0.0005

 

0.00934

Urinary bladder wall

  

0.01350

0.03820

Uterus

0.0006

 

0.01140

0.01320

Whole body

  

0.02560

0.01730

Effective dose

  

0.0308

0.0191