Fig. 2

Typical autoradiograms of the brain obtained at 60 min after [³H]hydromethidine injection to mice. Typical autoradiograms of the brain after intravenous injection of [³H]hydromethidine to mice treated with saline or DMTU (200 mg/kg, i.p.) 30 min before tMCAO (90 min). Coronal sections at the level of the striatum and hippocampus were prepared at 1, 2, 5, and 7 h after ischemia/reperfusion of MCA in mice. Regions of interest (ROIs) were marked on the MRI-T2 images in order to quantify the radioactivity concentration