VOI

Without resolution modelling

With resolution modelling


Correlation between
K
* and
K
,
r

Relative deviation of
K
* from
K

Correlation between
K
* and
K
,
r

Relative deviation of
K
* from
K


AortaVOI1

0.878

−0.044 ± 0.039

0.866

0.016 ± 0.061

(p < 0.01)

(p = 0.28)

(p < 0.01)

(p = 0.79)

AortaVOI2

0.914

−0.076 ± 0.033

0.889

−0.047 ± 0.050

(p < 0.01)

(p < 0.05)

(p < 0.01)

(p = 0.37)

AortaVOI3

0.858

0.071 ± 0.061

0.832

0.143 ± 0.091

(p < 0.01)

(p = 0.27)

(p < 0.01)

(p = 0.14)

AortaVOI4

0.882

0.066 ± 0.057

0.848

0.142 ± 0.088

(p < 0.01)

(p = 0.26)

(p < 0.01)

(p = 0.13)

VentricleVOI

0.819

0.141 ± 0.088

0.904

0.044 ± 0.046

(p < 0.01)

(p = 0.13)

(p < 0.01)

(p = 0.35)


K* = hepatic systemic clearance of ^{18}FFDGal (ml blood/ml liver tissue/min) estimated using imagederived input function; K = hepatic systemic clearance of ^{18}FFDGal (ml blood/ml liver tissue/min) estimated using timeactivity curve from manual blood sampling from the radial artery; VOI = volume of interest (see Figure 1 for details on each VOI definition). r = Pearson correlation coefficient for correlation between individual pairs of K* and K; p < 0.05 is considered to indicate statistically significant correlation. Relative deviation of K* from K is presented as mean ± SEM; mean deviation with p < 0.05 is considered statistically significantly different from zero.