Skip to main content

Advertisement

Table 2 Results of validation of HPLC versus ITLC (presented as 100% minus impurity B)

From: GMP-compliant 68Ga radiolabelling in a conventional small-scale radiopharmacy: a feasible approach for routine clinical use

Sample Percentage of Ga-68-DOTA-NOC (HPLC) Percentage of Ga-68-DOTA-NOC (ITLC 1) Percentage of Ga-68-DOTA-NOC (ITLC 2)
Validation 1 98.2 98.3 98.5
Validation 2 98.1 98.0 98.3
Validation 3 98.7 99.2 98.5
Spike 5% 93.7 94.5 91.4
Spike 10% 89.5 89.9 89.6
Spike 15% 84.8 85.2 87.6