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Table 3 Patient injected radioactivity and mass of [ 11 C]lapatinib

From: Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer

Subject number Brain metastases Time lapse after previous cranial RT (weeks) Scan day Injected activity (MBq) Radiotracer mass (μg)
1 No NA Baseline 44 1.16
  Day 8 148 4.45
3 No NA Baseline 69 4.47
  Day 8 288 5.21
4 Yes 70 Baseline 104 2.26
  Day 8 229 3.77
7 Yes 5 Baseline 349 12.39
  Day 8 167 6.85
9 No NA Baseline 222a 6.73
  Day 8 139 5.50
10 Yes 11 Baseline -b -
  Day 8 114 4.65
  1. aData not included in analysis due to tissue extravasation of radiotracer injection. bSubject was unable to have baseline scan due to radiochemistry failure. MBq, megabecquerel; NA, not applicable as patients did not have brain metastases.